Purpose: Spasm of the near reflex (SNR) is a triad of miosis, excess accommodation and excess convergence.Primary SNR is most often functional in origin We aim to highlight the clinical features which distinguish primary convergence from other conditions with a similar presentation but more sinister underlying aetiology, for example bilateral abduc
LegacyClimate 1.0: a dataset of pollen-based climate reconstructions from 2594 Northern Hemisphere sites covering the last 30 kyr and beyond
Here we describe LegacyClimate 1.0, a dataset of the reconstruction of the mean July temperature (TJuly), mean annual temperature (Tann), and annual precipitation (Pann) from 2594 fossil pollen records from the Northern Hemisphere, spanning the entire Holocene, with some records reaching back to the Last Glacial Period.Two reconstruction methods, t
From Chaos to Opportunity: Decoding Cancer Heterogeneity for Enhanced Treatment Strategies
Cancer manifests as a multifaceted disease, characterized by aberrant cellular proliferation, survival, migration, and invasion.Tumors exhibit variances across diverse dimensions, encompassing genetic, epigenetic, and transcriptional realms.This heterogeneity poses significant challenges in prognosis and treatment, affording tumors advantages throu
CUZD1 is a critical mediator of the JAK/STAT5 signaling pathway that controls mammary gland development during pregnancy.
In the mammary gland, genetic circuits controlled by estrogen, progesterone, and prolactin, act in concert with pathways regulated by members of the epidermal growth factor family to orchestrate growth and morphogenesis during puberty, pregnancy and lactation.However, the precise mechanisms underlying the crosstalk between the hormonal and Boombox
Evaluation of Business Model Development through Customer Discovery Approach (Case Study of PT Hijup.com)
Objectives: Islamic fashion e-commerce grows rapidly in Indonesia.Hijup.com is the pioneer and the biggest player in the industry.In order to ZESTY ORANGE thrive in fiercer competition, Hijup.com needs to improve its business model.The study aims to seek a more suitable business model for Hijup.com using customer development approach.Method: The re